Cryptococcal Antigen Screen, Serum or Spinal Fluid
Code: 8300
Keywords/Mnemonics: crypto
Updated: 02/23/2011
| Specimen Required: |
Submit one of the following:
Serum 1 plain red top serum tube or 1 gold top serum gel tube. Send 1.0 mL of serum removed from the fully clotted whole blood (plain red or serum gel tube) and transferred to a sterile labeled tube.
CSF 1.0 mL cerebrospinal fluid (CSF).should be aseptically collected and transferred to a sterile labeled screw-top tube.
Store/transport specimen refrigerated.
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| Patient Prep: | None |
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| Reference Values: |
Negative
Positive Results will automatically reflex a titer.
Critical Value: Positive results
IMPORTANT NOTE: "Cryptococcus gattii is an emerging agent of cryptococcosis that is indistinguishable from C. neoformans by most routine laboratory tests, including the Cryptococcal Antigen test." ASM-A Quick Guide to the Significance and Laboratory Identification of Cryptococcus gattii, January 18, 2011.
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| Days Performed: | Daily |
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| Days Reported: | Daily |
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| Interference: | Trichosporon beigelii has been shown to produce a cross-reactive poly-saccharide antigen. |
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| Rejection: | |
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| Methodology: | Latex Agglutination |
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| CPT Code(s): |
86403 - Particle agglutination, screen
86406 - Titer, each antibody
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